I-Neomycin sulphate 70% yomgubo onyibilikayo wamanzi
I-Neomycin sulphate 70% yomgubo onyibilikayo wamanzi
UCHAWULO:
Iqulethe ngegram nganye:
Neomycin sulphate……………………….70 mg.
Intengiso yomphathi …………………………………….1 g.
INGCACISO:
I-Neomycin sisibulali-zintsholongwane esine-spectrum esibanzi se-bactericidal aminoglycosidic esisebenza ngokukodwa kumalungu athile e-Enterobacteriaceae umz. Escherichia coli. Indlela yayo yokusebenza ikwinqanaba le-ribosomal. Xa ilawulwa ngomlomo, i-fraction kuphela (<5%) ifunnwe ngokwenkqubo, intsalela ihlala njengesixhobo esisebenzayo kwi-gastro-intestinal tract yesilwanyana. I-Neomycin ayenziwanga isebenze ngee-enzymes okanye ukutya. Ezi mpawu ze-pharmacological zikhokelela ekubeni i-neomycin ibe sisibulala-zintsholongwane esisebenzayo kuthintelo nakunyango losulelo lwe-enteric olubangelwa yibhaktiriya ebuthathaka kwi-neomycin.
IIzalathisi:
Iboniswa kuthintelo kunye nokunyangwa kwe-bacterial enteritis kumathole, iigusha, iibhokhwe, iihagu kunye neenkukhu ezibangelwa iibhaktheriya ezithintekayo kwi-neomycin, njenge-E. coli, i-Salmonella kunye ne-Campylobacter spp.
IZITHINTELO
Hypersensitivity kwi-neomycin.
Ulawulo kwizilwanyana ezinokukhubazeka okukhulu komsebenzi wezintso.
Ulawulo kwizilwanyana ezine-microbial digestion esebenzayo.
Ulawulo ngexesha lokumitha.
Ulawulo kwiinkukhu ezivelisa amaqanda ukuze zityiwe ngabantu.
IMIPHUMELA:
I-Neomycin yeziphumo eziyityhefu eziqhelekileyo (i-nephrotoxicity, ubuthulu, i-neuromuscular blockade) ayiveli ngokubanzi xa ilawulwa ngomlomo. Akukho ziziphumo ebezingalindelekanga ezongezelelweyo ekufuneka zilindelwe xa irejimeni yedosi emiselweyo ilandelwa ngokuchanekileyo.
UMGANGATHO NOKULAWULWA:
Kulawulo lomlomo:
Iinkukhu : 50-75 mg Neomycin sulphate ilitha nganye yamanzi okusela kangangeentsuku ezi-3 ukuya kwezi-5.
Qaphela: kusenzelwa amathole, amatakane kunye namatakane asele etyetyisiwe kuphela.
IXESHA LOKURHOXA:
- Yenyama:
Amathole, iibhokhwe, iigusha neehagu : Iintsuku ezingama-21.
Iinkukhu : iintsuku ezisi-7.