Unyango losulelo lwesikhumba, usulelo lwendlela yomchamo, usulelo lwendlela yokuphefumla, usulelo lwesisu kunye nosulelo lomlomo ezinjeni.

UHLELO

Ithebhulethi nganye ine:
Amoxicillin (njenge-amoxicillin trihydrate) 250 mg
I-Clavulanic acid (njenge-potassium clavulanate) 62.5 mg

 Izalathiso zokusetyenziswa, ukucacisa uhlobo ekujoliswe kulo

Unyango losulelo kwizinja ezibangelwa ziibhaktheriya ezibuthathakaamoxicillin kudityaniswe ne-clavulanic acid, ngakumbi: Usulelo lwesikhumba (kubandakanya i-pyyodermas engaphezulu kunye nenzulu) eyayanyaniswa ne-Staphylococci (kubandakanywa neentlobo ezivelisa i-beta-lactamase) kunye ne-Streptococci.
Usulelo lomjelo womchamo olunxulunyaniswa ne-Staphylococci (kuquka iintlobo ezivelisa i-beta-lactamase), i-Streptococci, i-Escherichia coli (ibandakanya iintlobo ezivelisa i-beta-lactamase), i-Fusobacterium necrophorum kunye ne-Proteus spp.
Usulelo lwendlela yokuphefumla ehambelana ne-Staphylococci (kubandakanywa ne-beta-lactamase evelisa iintlobo), i-Streptococci kunye ne-Pasteurellae.
Usulelo lwendlela yesisu enxulumene ne-Escherichia coli (kuquka i-beta-lactamase evelisa iintlobo) kunye ne-Proteus spp.
Usulelo lomlomo womlomo (i-mucous membrane) ehambelana ne-Clostridia, i-Corynebacteria, i-Staphylococci (kubandakanywa ne-beta-lactamase evelisa iintlobo), i-Streptococci, i-Bacteroides spp (kubandakanywa ne-beta-lactamase evelisa iintlobo), i-Fusobacterium necrophorum kunye ne-Pasteurellae.

Umthamo
I-dose ephakanyisiweyo yi-12.5 mg yezinto ezidibeneyo ezisebenzayo (=10 mgamoxicillinkunye ne-2.5 mg clavulanic acid) ngekhilogram yobunzima bomzimba, kabini yonke imihla.
Le theyibhile ilandelayo ijongwe njengesikhokelo sokuhambisa imveliso kwizinga ledosi esemgangathweni ye-12.5 mg ye-active actives per kg bodyweight kabini imihla ngemihla.
Kwiimeko eziphikisayo zosulelo lwesikhumba, idosi ephindwe kabini iyacetyiswa (25 mg ngekhilogram yobunzima bomzimba, kabini yonke imihla).

Iimpawu ze-Pharmacodynamic

I-Amoxicillin/clavulanate inoluhlu olubanzi lwemisebenzi equka i-βlactamase evelisa iintlobo ze-Gram-positive kunye ne-Gram-negative aerobes, i-facultative anaerobes kunye ne-obligate anaerobes.

Ukungenwa kakuhle kuboniswa ngeebhaktheriya ezininzi zegram-positive kuquka i-Staphylococci (kubandakanywa ne-beta-lactamase evelisa iintlobo, i-MIC90 0.5 μg / ml), i-Clostridia (MIC90 0.5 μg / ml), i-Corynebacteria kunye ne-Streptococci, kunye ne-gram-negative bacteria equka i-Bacteropps i-betalactamase evelisa iintlobo, i-MIC90 0.5 μg / ml), i-Pasteurellae (MIC90 0.25 μg / ml), i-Escherichia coli (kubandakanywa ne-beta-lactamase evelisa iintlobo, i-MIC90 8 μg / ml) kunye ne-Proteus μ0g/mIC (MIC9 spp.5). Ukuchaphazeleka okuguquguqukayo kufumaneka kwezinye i-E. coli.

Beka ubomi kwishelufa
Ubomi beshelufa yemveliso yonyango lwezilwanyana njengoko ipakishwe ukuthengiswa: iminyaka emi-2.
Ubomi beshelufu yeekota zeethebhulethi: iiyure ze-12.

Izilumkiso ezikhethekileyo zokugcina
Musa ukugcina ngaphezu kwe-25°C.
Gcina kwisikhongozeli sokuqala.
Iipilisi zekota kufuneka zibuyiselwe kumgca ovulekileyo kwaye zigcinwe efrijini.